办公地点

吉林大学第一医院

办公电话

0431-88782480

邮箱

zhsixi@163.com

教育背景

2015-2019 吉林大学 博士研究生

2004-2007 山东大学 硕士研究生 

2000-2004 山西医科大学 本科生

工作经历

2008-2024,吉林大学第一医院临床药学部,主任

2021-2024,吉林大学, 药学院药物治疗学教研室, 副教授/硕士生导师

主讲课程

临床心理学沟通与技巧、药学服务与咨询

研究领域

药物经济学、临床用药评价、药物新剂型及体内代谢动力学

科研成果

发表第一或通讯作者学术论文55篇（SCI论文16篇）；参编书籍2部；第一发明人申报发明专利1项；主持吉林省科技创新专项等课题10余项。 部分代表作： （文章）：1.XingNaoJing injection ameliorates cerebral ischaemia/reperfusion injury via SIRT1-mediated inflammatory response inhibition. 2.The evaluation of hepatoprotective effects of flavonoids from Scorzonera austriaca Wild against CCl 4-induced acute liver injury in vitro and in vivo. 3.XingNaoJing injections protect against cerebral ischemia/reperfusion injury and alleviate blood-brain barrier disruption in rats, through an underlying mechanism of NLRP3 inflammasomes suppression. 4.Salvianolic Acid B Attenuates Apoptosis of HUVEC Cells Treated with High Glucose or High Fat via Sirt1 Activation. 5.Astragaloside IV protects against cisplatin-induced liver and kidney injury via autophagy-mediated inhibition of NLRP3 in rats. 6.Salvianolic acid inhibits the effects of high glucose on vascular endothelial dysfunction by modulating the Sirt1-eNOS pathway. 7.Autophagy inhibition‐enhanced assembly of the NLRP3 inflammasome is associated with cisplatin‐induced acute injury to the liver and kidneys in rats. 8. Xingnaojing Injection Protects against Cerebral Ischemia Reperfusion Injury via PI3K/Akt-Mediated eNOS Phosphorylation. 9. Efficacy and safety of ceftazidime-avibactam in the treatment of complicated intra-abdominal infections (CIAIs) and complicated urinary tract infections (CUTIs):A meta-analysis of randomized controlled trials. 10.Development of an LC/MS method for quantificationg of two pairs of isomeric flavonoid glycosides and other ones in rat plasma:Application to pharmacokenetic studies （课题）1.鲜龙葵果配方颗粒国家标准研究及产业化开发，吉林省财政厅，经费50万，项目负责人； 2.山茄子提取物及单体成分抗乙肝病毒活性研究，吉林省财政厅，经费15万，项目负责人； 3.基于代谢组学研究杜仲抗高血压药效物质基础及作用机制 ，吉林省财政厅，经费15万，项目负责人； （专利）吡嘧司特钾温度敏感性水凝胶及其制备方法，ZL201510507221.2，2018.8.31，第一发明人。