Address

Room 204, School of Pharmacitical Science

Tel.

0431-85619716

Email

jguo@jlu.edu.cn

Education Background

2001-2005 BSc, Bioscience, School of Life Sciences, Northeast Normal University

2005-2007 MSc, Biotechnology, Department of Biochemistry, University College Cork

2007-2011 PhD, Pharmacy, School of Pharmacy, University College Cork

Work Experience

2018- Professor & Doctoral Supervisor, School of Pharmaceutical Sciences, Jilin University

2018-2020 Visiting Scholar, Eshelman School of Pharmacy, UNC at Chapel Hill

2016-2017 Professor & Masters Supervisor, School of Pharmaceutical Sciences, Jilin University

2013-2016 Government of Ireland Research Fellow, School of Pharmacy, University College Cork

2012-2013 Study Director, Department of Pharmacology, Viva Biotech Ltd.

2011-2012 Postdoctoral Researcher, School of Medicine, University of Michigan

Courses

Pharmaceutics of Biological Drugs; English for Pharmaceutical Sciences

Research Field

Nano Drug Delivery Systems; Tumor Immunotherapy; Tissue Regeneration

Scientific Research Achievements

Publications:

1. Guo J, Huang L*. Formulation of two lipid-based membrane-core nanoparticles for FOLFOX combination therapy. Nature Protocols 2022, 17: 1818-1831.

2. Han S, Bi S, Guo T, Sun D, Zou Y, Wang L, Song L, Chu D, Liao A, Song X, Yu Z*, Guo J*. Nano co-delivery of plumbagin and dihydrotanshinone I reverses immunosuppressive TME of liver cancer. Journal of Controlled Release 2022, 348: 250-263.

3. Sun D, Zou Y, Song L, Han S, Yang H, Chu D, Dai Y, Ma J, O'Driscoll CM, Yu Z*, Guo J*. A cyclodextrin-based nanoformulation achieves co-delivery of ginsenoside Rg3 and quercetin for chemo-immunotherapy in colorectal cancer. Acta Pharmaceutica Sinica B 2022, 12: 378-393.

4. Guo J, Yu Z, Sun D, Zou Y, Liu Y, Huang L*. Two nanoformulations induce reactive oxygen species and immunogenetic cell death for synergistic chemo-immunotherapy eradicating colorectal cancer and hepatocellular carcinoma. Molecular Cancer 2021, 20: 10.

5. Yang H#, Song L#, Sun B, Chu D, Yang L, Li M, Li H, Dai Y, Yu Z, Guo J*. Modulation of macrophages by a paeoniflorin-loaded hyaluronic acid-based hydrogel promotes diabetic wound healing. Materials Today Bio 2021, 12: 100139.

Patents for Inventions:

1. J Guo, Y Gao, T Anastassiades. Hyaluronic Acid Derivatives for Wound Healing. 2020, PCT/CA2020/000022.

2. L Huang, J Guo. Delivery System Complexes comprising a Precipitate of An Active Agent and Methods of Use. 2022, PCT/US20/55424.