Sun Kai

author: Time:2023-04-04 Number of hits:

Name

Kai Sun

Title

Associate Professor;master supervisor

Address

Room 405; Building of regeneration

Tel.

15243127340

Email

thomassk@jlu.edu.cn

Education Background

1997-2005,Shenyang pharmaceutical university,Bachlor,Master,Ph.D.

Work Experience

2008-,associate professor & master superviser,School of Pharmaceutical Science, Jilin University; 2007-2008, Post-doc fellowship, Nagoya University; 2005-2007, Invited researcher, Meijo University

Courses

Natural products chemistry; Spectrometric identification

Research Field

1、organic synthesis and catalysis based on green chemistry and atom economy; 2、medicinal chemistry based on green chemistry and industrial production; 3、research on structure-activity relationship of active leader compounds;

4、resurses of traditional medicine and active natural products;

5、mechanism research of serious decease based on fluorescence probes in living body

Scientific Research Achievements

Publictions:

1. Sun, K.; Li, X.; Li, W.; Liu, J.M.; Wang, J.H.; Sha, Y. Two new lactones and one new aryl-8- oxa-bicyclo[3,2,1]oct-3-en-2-one from Descurainia Sophia, Chemical and Pharmaceutical Bulletin , 2004,52(12),1483-1486.

2. Sun, K., Li, X. Liu, J.M., Wang, J.H., Li, w., Sha, Y. Two new compounds from the seeds of Descurainia Sophia. Die Pharmazie,2005,60(9),717-718.

3. Sun, K.; Li, X.; Liu, J.M.; Wang, J.H.; Li, W.; Sha, Y., 2004. A novel sulphur glycoside from the seeds of Descurainia sophia (L.). Journal of Asian Natural Products Research,2005,7(6),853-856.

4. Sun, K.; Li, X.; Li, W.; Liu, J.M.; Wang, J.H.; Sha, Y., A new nor-lignan from the seeds of Descurainia Sophia. Natural Products Research,2006,20(6),519-522.

5. J. Yang, X. Liu, D.-L. Meng, H.-Y. Chen, Z.-H. Zong, T.-T. Feng, K. Sun, Efficient iron-catalyzed direct β-alkylation of secondary alcohols with primary alcohols, Adv. Synth. Catal. 2012, 354, 328-334.(Impact Factor: 6.453)

6. Yanwei Sun, Haiyang Jiang, Hao Tang, Haixia Xu, Huiling Liu, Kai Sun,∗ and Xuri Huang,Theoretical investigation on the mechanism of FeCl3-catalysed cross- coupling reaction of alcohols with alkenes,Molecular Physics 2014, 112 (16), 2107–2113.( Impact Factor:1.720)

7. Pei-yu Qin , Wei Feng , Rui Wang , Huan-yu Zhao , Hui-ling Liu* , Xu-ri Huang , Kai Sun*,theoretical investigation on the mechanism of ferrocenecarbox- aldehyde catalyzed direct b-alkylation of 1-phenylethanol with benzyl alcohol,Polyhedron 2016,111 ,179–184(Impact Factor:1.843)。

8. Wei Feng, Junfeng Zhao, Aiwen Wei, Dandan Zhang, Huiling Liu, *Xuri Huang* and Kai Sun*,The theoretical chemical calculations clarify the mechanism of beta-alkylation of 1-phenylethanol with benzyl alcohol catalyzed by iron(II) acetylacetonate methods,RSC Adv., 2018, 8, 24154–24165;

9. Jing Tan, Junli Liu, Han Wang, Ying Zhang, Hongqiang Lin, Zhongyao Wang,Hanrui Si, Yutong Zhang, Jinping Liu, * Pingya Li* and Kai Sun*,Identification of blood-activating components from Xueshuan Xinmaining Tablet based on the spectrum–effect relationship and network pharmacology analysis,RSC Adv., 2020, 10, 9587–9600;

10. 孙凯,李铣,2003。南葶苈子中的一个新黄酮苷。中国药物化学杂志,13(4),233,248。

11. 孙凯,李铣,2003。南葶苈子的化学成分。沈阳药科大学学报,20(6), 419-421

12. 孙凯,李铣,康兴东,刘丽,2005。南葶苈子的化学成分。沈阳药科大学学报,22(3), 181-182

13. 孙凯,李铣,2002。葶苈子化学成分及药理作用的研究进展。中草药,33(7),附3-附5。

14. 陈滴,刘昕,杨晓虹,孙凯(通许作者),2010。南葶苈子化学成分研究。特产研究,32(2):62-63,77。

15. 宗智慧, 冯亭亭, 陈红艳, 白 芳, 冯 岩, 孙 凯(通讯作者),2011,中西医结合治疗高血压的研究进展,中西医结合心脑血管病杂志,9(8):990-991.

16. 王小禹, 宗智慧, 李杰, 徐海丽, 孙凯(通讯作者),2014。2-(咪唑并[1,2-a]吡啶-3-基)乙酸的合成工艺改进。中国药物化学杂志,23(1):34-36。

Patents for inventions:

1. 发明人:孙凯,杨健,申请人:吉林大学,一种1,3-二苯基-1-丙醇类化合物的合成方法,专利号:201010107852.2。

2. 发明人:孙凯,贾妍,成焕吉,宗智慧,冯亭亭,王小禹,李杰,申请人:吉林大学,一种双膦酸类化合物的制备方法,专利号:201210186236.X。

3. 发明人:孙凯,尹嘉宁,孙璐璐,赵文成,张晓辰,焦魁良,齐军彩,刘延福,赵楠,胡巧凤;一种N-乙基-3-苯基丙胺的制备方法;专利号:201810527640.6;

4. 发明人:孙凯,李亚男,赵文成,张晓辰,王熙玮,田立,吴鑫星,焦魁良,张亚非,杨蕾,一种降低阿尔维林中N-乙基-3-苯基丙胺残留的方法,专利号:201810527636.X;

5. 发明人:孙凯,乔红梅,赵云鹏,孙璐璐,王熙玮,井亚坤,韩春景,李园园,郭聪聪,杨孟,一种N-乙基-3-苯基丙胺的纯化方法,专利号:201810527637.4。

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