Name |
Pingya Li |
Title |
Professor |
|
Address |
Room 124, School of Basic Medical |
Tel. |
0431-85619803 |
Email |
lipy@jlu.edu.cn |
Education Background |
1978-1983 Bachelor, Chemistry, Sichuan University 1983-1985 Master, School of Basic Medical Sciences, Norman Bethune Medical University 1994-1999 Ph.D., Traditional Chinese Medicine, Shenyang Pharmaceutical University |
Work Experience |
2000- Professor & doctoral supervisor, School of Pharmacitical Science, Jilin University 2015- Director, National and Local Joint Engineering Research Center for Ginseng Innovative Drug Development in Jilin Province 2017- Director, Natural Medicine Research Center of Jilin University 1999-2000 Professor, School of Basic Medical Sciences, Norman Bethune Medical University 1988-1994 Vice Professor & master supervisor, School of Basic Medical Sciences, Norman Bethune Medical University 1983-1985 Assistant Professor, School of Basic Medical Sciences, Norman Bethune Medical University |
Courses |
|
Research Field |
Chemical constituents and biological activities of natural medicines; Structural modifications; Quality control; New drug Invention |
Scientific Research Achievements |
Publications: |
Journals: |
1. WANG, C. Z., YUAN, Y. Z., PAN, H., HSU, A. C. Y., CHEN, J. L., LIU, J. P.,LI, P. Y.& WANG, F.*2020. Protective Effect of Ocotillol, the Derivate of Ocotillol-Type Saponins in Panax Genus, against Acetic Acid-Induced Gastric Ulcer in Rats Based on Untargeted Metabolomics.International Journal of Molecular Sciences,21,2577. |
2. FU, T. H., LIU, X. F., LIU, J. P., CAI, E. B., ZHAO, Y.*, LI, H. J., ZHANG, L. X.,LI, P. Y.& GAO, Y. G. 2020. alpha-Mangostin exhibits antidepressant-like effects mediated by the modification of GABAergic, serotonergic and dopaminergic systems.Natural Product Research,34,868-871. |
3. TAN, J., LIU, J. L., WANG, H., ZHANG, Y., LIN, H. Q., WANG, N. Y., SI, H. R., ZHANG, Y. T., LIU, J. P.*,LI, P. Y.*& SUN, K.*2020. Identification of blood-activating components from Xueshuan Xinmaining Tablet based on the spectrum-effect relationship and network pharmacology analysis.Rsc Advances,10, 9587-9600. |
4. YANG, N., WANG, H., LIN, O. Q., LIU, J. L., ZHOU, B. S., CHEN, X. L., WANG, C. Z., LIU, J. P.*&LI, P. Y.*2020. Comprehensive metabolomics analysis based on UPLC-Q/TOF-MSE and the anti-COPD effect of different parts ofCelastrus orbiculatus Thunb.Rsc Advances,10,8396-8420. |
5. WANG, C. Z., DONG, Q. H., WU, F. L., LI, Z.,LI, P. Y., LIU, J. P. & WANG, F.*2020. A new alkynol compound fromPlatycodins foliumand its cytotoxicity.Natural Product Research,7. |
6. ZHENG, Q., WANG, R. L., ZHANG, N. Q., WANG, C. Z. &LI, P. Y.*2020. In vivo pharmacokinetics, distribution, and excretion of an anticancer agent isolated from red ginseng, in rat.Xenobiotica,50, 1323-1331. |
7. QI, Z., WANG, Z., ZHOU, B., FU, S., HONG, T.,LI, P. Y.*& LIU, J. P.*2020. A new ocotillol-type ginsenoside from stems and leaves ofPanax quinquefoliumL. and its anti-oxidative effect on hydrogen peroxide exposed A549 cells.Natural Product Research,34, 2474-2481. |
8. LIN, H. Q., ZHU, H. L., TAN, J., WANG, H., WANG, Z. Y.,LI, P. Y.*, ZHAO, C. F.*& LIU, J. P.*2019. Comparative Analysis of Chemical Constituents ofMoringa oleiferaLeaves from China and India by Ultra-Performance Liquid Chromatography Coupled with Quadrupole-Time-Of-Flight Mass Spectrometry.Molecules,24,25. |
9. LIN, H. Q., ZHU, H. L., TAN, J., WANG, H., DONG, Q. G., WU, F. L., LIU, Y. H.,LI, P. Y.*& LIU, J. P.*2019. Non-Targeted Metabolomic Analysis of Methanolic Extracts of Wild-Simulated and Field-Grown American Ginseng.Molecules,24,25. |
10. QI, Z., LI, Z., GUAN, X. W., WANG, C. Z., WANG, F.,LI, P. Y.*& LIU, J. P.*2019. Four Novel Dammarane-Type Triterpenoids from Pearl Knots ofPanax ginseng Meyer cv. Silvatica.Molecules,24,13. |
11. WANG, C. Z., LIN, H. Q., YANG, N., WANG, H., ZHAO, Y.,LI, P. Y., LIU, J. P.*& WANG, F.* 2019. Effects ofPlatycodins Foliumon Depression in Mice Based on a UPLC-Q/TOF-MS Serum Assay and Hippocampus Metabolomics.Molecules,24, 20. |
12. LIN, H. Q., ZHU, H. L., TAN, J., WANG, C. Z., DONG, Q. H., WU, F. L., WANG, H., LIU, J. L.,LI, P. Y.*& LIU, J. P.* 2019. Comprehensive Investigation on Metabolites of Wild-Simulated American Ginseng Root Based on Ultra-High-Performance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry.Journal of agricultural and food chemistry,67,5801-5819. |
13. QI, Z., LI, W., TAN, J., WANG, C. Z., LIN, H. Q., ZHOU, B. S., LIU, J. P. &LI, P. Y.*2019. Effect of ginsenoside Rh2 on renal apoptosis in cisplatin-induced nephrotoxicity in vivo.Phytomedicine, 61,14. |
14. ZHANG, K., LIU, Y., WANG, C. Z., LI, J. N., XIONG, L. X., WANG, Z. Z., LIU, J. P.*&LI, P. Y.*2019. Evaluation of the gastroprotective effects of 20 (S)-ginsenoside Rg3 on gastric ulcer models in mice.Journal of Ginseng Research,43,550-561. |
15. WU, D., WANG, H., TAN, J., WANG, C., LIN, H., ZHU, H., LIU, J. P.,LI, P. Y.& YIN, J. Y.*2019. Pharmacokinetic and Metabolism Studies of Curculigoside C by UPLC-MS/MS and UPLC-QTOF-MS.Molecules,24. |
16. ZHU, H. L., LIU, J. L., LIN, H. Q., ZHANG, Y., YANG, N., ZHOU, B. S., WANG, Z. Y., HSU, A. C. Y., LIU, J. P.*&LI, P. Y.*2019. UPLC-QTOF-MS-guided isolation of anti-COPD ginsenosides from wild ginseng.Rsc Advances,9, 38658-38668. |
17. QI, Z., CHEN, L. X., LI, Z., SHAO, Z. J., QI, Y. L., GAO, K., LIU, S. X., SUN, Y. S.*,LI, P. Y. & LIU, J. P.*2019. Immunomodulatory Effects of (24R)-Pseudo-Ginsenoside HQ and (24S)-Pseudo-Ginsenoside HQ on Cyclophosphamide-Induced Immunosuppression and Their Anti-Tumor Effects Study.International journal of molecular sciences,20,836. |
18. YIN, Y. X., ZHANG, Y. G., LI, H. J., ZHAO, Y., CAI, E. B., ZHU, H. Y.,LI, P. Y.& LIU, J. P.*2019. Triterpenoids from fruits ofSorbus pohuashanensisinhibit acetaminophen-induced acute liver injury in mice.Biomedicine & Pharmacotherapy,109,493-502. |
19. ZHU, H. L., LIN, H. Q., TAN, J., WANG, C. Z., QANG, H., WU, F. L., DONG, Q. H., LIU, Y. H.,LI, P. Y.*& LIU, J. P.* 2019. UPLC-QTOF/MS-Based Nontargeted Metabolomic Analysis of Mountain- and Garden-Cultivated Ginseng of Different Ages in Northeast China.Molecules,24,1-24. |
20. BIAN, X. B., LIU, X. F., LIU, J. P., ZHAO, Y., LI, H. J., ZHANG, L. X.*,LI, P. Y. & GAO, Y. G. 2019. Hepatoprotective effect of chiisanoside from Acanthopanax sessiliflorus against LPS/D-GalN-induced acute liver injury by inhibiting NF-B and activating Nrf2/HO-1 signaling pathways.Journal of the Science of Food and Agriculture,99, 3283-3290. |
21. RAN, N., PANG, Z. Q., GUAN, X. W., WANG, G. Q., LIU, J. P.,LI, P. Y., ZHENG, J. T. & WANG, F.*2019. Therapeutic Effect and Mechanism Study ofRhodiola wallichianavar. cholaensis Injection to Acute Blood Stasis Using Metabolomics Based on UPLC-Q/TOF-MS.Evidence-Based Complementary and Alternative Medicine,2019,20. |
22. CHEN, L. X., QI, Z., SHAO, Z. J., LI, S. S., QI, Y. L., GAO, K., LIU, S. X., LI, Z., SUN, Y. S.*&LI, P. Y.*2019. Study on Antidepressant Activity of Pseudo-Ginsenoside HQ on Depression-Like Behavior in Mice.Molecules,24,13. |
23. BIAN, X. B., WANG, S. J., LIU, J. P., ZHAO, Y.*, LI, H. J., ZHANG, L. X.*&LI, P. Y.2019. Hepatoprotective effect of chiisanoside against acetaminophen-induced acute liver injury in mice.Natural Product Research,33,2704-2707. |
24. ZHANG, Q. H., LI, X. Z., HAN, L.,LI, P. Y.& LU, D.*2018. Determination of Sophorabioside in Rat Plasma by UPLC-MS/MS and its Application to a Pharmacokinetic Study.Journal of Chromatographic Science,56,154-159. |
25. BIAN, X. B., LIU, X. F., LIU, J. P., ZHAO, Y.*, LI, H. J., CAI, E. B.,LI, P. Y. & GAO, Y. G.*2018. Study on antidepressant activity of chiisanoside in mice.International Immunopharmacology,57, 33-42. |
26. FU, T. H., WANG, S. J., LIU, J. P., CAI, E. B., LI, H. J.,LI, P. Y. & ZHAO, Y.*2018. Protective effects ofα-mangostin against acetaminophen-induced acute liver injury in mice.European journal of pharmacology,827, 173-180. |
27. YIN, Y. X., LIU, X. F., LIU, J. P., CAI, E. B., ZHU, H. Y.*, LI, H. J., ZHANG, L. X.,LI, P. Y.& ZHAO, Y.*2018. Beta-sitosterol and its derivatives repress lipopolysaccharide/D-galactosamine-induced acute hepatic injury by inhibiting the oxidation and inflammation in mice.Bioorganic & Medicinal Chemistry Letters,28,1525-1533. |
28. WANG, W. D., WANG, S. J., LIU, J. P., CAI, E. B., ZHU, H. Y.*, HE, Z. M., GAO, Y. G.,LI, P. Y.& ZHAO, Y.*2018. Sesquiterpenoids from the root ofPanax Ginsengprotect CCl4-induced acute liver injury by anti-inflammatory and anti-oxidative capabilities in mice.Biomedicine & Pharmacotherapy,102, 412-419. |
29. WANG, W. D., ZHANG, Y. G., LI, H. J., ZHAO, Y.*, CAI, E. B., ZHU, H. Y.,LI, P. Y. & LIU, J. P.*2018. Protective Effects of Sesquiterpenoids from the Root ofPanax ginsengon Fulminant Liver Injury Induced by Lipopolysaccharide/d‑Galactosamine.Journal of agricultural and food chemistry,66, 7758-7763. |
30. WANG, Y. R., WANG, C. Z., LIN, H. Q., LIU, Y. H., LI, Y. M., ZHAO, Y.,LI, P. Y.& LIU, J. P.*2018. Discovery of the Potential Biomarkers for Discrimination betweenHedyotis diffusa andHedyotis corymbosa by UPLC-QTOF/MS Metabolome Analysis.Molecules,23, 1525-1549. |
31. TAN, J., WANG, C. Z., ZHU, H. L., ZHOU, B. S., XIONG, L. X., WANG, F.,LI, P. Y.*& LIU, J. P.*2018. Comprehensive Metabolomics Analysis of Xueshuan Xinmaining Tablet in Blood Stasis Model Rats Using UPLC-Q/TOF-MS.Molecules,23,16. |
32. YIN, Y. X., LIU, X. F., LIU, J. P., CAI, E. B., ZHAO, Y.*, LI, H. J., ZHANG, L. X.,LI, P. Y.& GAO, Y. G.*2018. The effect of beta-sitosterol and its derivatives on depression by the modification of 5-HT, DA and GABA-ergic systems in mice.Rsc Advances,8,671-680. |
33. FU, T. H., LI, H. J., ZHAO, Y.*, CAI, E. B., ZHU, H. Y.,LI, P. Y.& LIU, J. P.* 2018. Hepatoprotective effect of alpha-mangostin against lipopolysaccharide/D-galactosamine-induced acute liver failure in mice.Biomedicine & Pharmacotherapy, 106,896-901. |
34. QI, Z., LI, Z., LI, W., LIU, Y., WANG, C., LIN, H., LIU, J. P. &LI, P. Y.*2018. Pseudoginsengenin DQ Exhibits Therapeutic Effects in Cisplatin-Induced Acute Kidney Injury via Sirt1/NF-κB and Caspase Signaling Pathway without Compromising Its Antitumor Activity in Mice.Molecules (Basel, Switzerland),23,3038. |
35. WANG, W. D., LIU, X. F., LIU, J. P., CAI, E. B., ZHAO, Y.*, LI, H. J., ZHANG, L. X.,LI, P. Y.& GAO, Y. G.*2018. Sesquiterpenoids from the Root ofPanax ginsengAttenuates Lipopolysaccharide-lnduced Depressive-Like Behavior through the Brain-Derived Neurotrophic Factor/Tropomyosin-Related Kinase B and Sirtuin Type 1/Nuclear Factor-kappa B Signaling Pathways.Journal of agricultural and food chemistry,66,265-271. |
36. WANG, Z. Z., LIN, H. Q., ZHU, H. L., YANG, N., ZHOU, B. S., WANG, C. Z.,LI, P. Y.*& LIU, J. P.*2018. Pharmacokinetic and Metabolism Studies of 12-Riboside-Pseudoginsengenin DQ by UPLC-MS/MS and UPLC-QTOF-MSE.Molecules,23,15. |
37. WANG, C. Z., ZHANG, N. Q., WANG, Z. Z., QI, Z., ZHENG, B. Z.,LI, P. Y.*& LIU, J. P.*2017. Rapid characterization of chemical constituents ofPlatycodon grandiflorumand its adulterantAdenophora strictaby UPLC-QTOF-MS/MS.J. Mass Spectrom,52,643-656. |
38. ZHANG, N. Q., WANG, C. Z., WANG, Z. Z., LI, Z., SAI, J. Y., MENG, Y., WANG, F., LI, P. Y.*& LIU, J. P.*2017. Anti-myocardial ischaemic effect of pseudoginsenoside F11 by inhibiting expression of beta1-adrenoceptor in rats with coronary artery ligation.Journal of functional foods,36, 224-232. |
39. WANG, C. Z., ZHANG, N. Q., WANG, Z. Z., QI, Z., ZHU, H. L., ZHENG, B. Z.,LI, P. Y.*& LIU, J. P.*2017. Nontargeted Metabolomic Analysis of Four Different Parts ofPlatycodon grandiflorumGrown in Northeast China.Molecules,22,16. |
40. BIAN, X., ZHAO, Y.*, GUO, X., ZHANG, L., LI, P., FU, T., WANG, W., YIN, Y., CHEN, G. & LIU, J. P.*2017. Chiisanoside, a triterpenoid saponin, exhibits anti-tumor activity by promoting apoptosis and inhibiting angiogenesis.Rsc Advances,7,41640-41650. |
41. XIONG, L. X., QI, Z., ZHENG, B. Z., LI, Z., WANG, F., LIU, J. P.*& LI, P. Y.*2017. Inhibitory Effect of Triterpenoids fromPanax ginsengon Coagulation Factor X.Molecules,22,649-655. |
42. LIU, X. J., XING, H. C., GAO, W. J., YU, D., ZHAO, Y. M., SHI, X. J., ZHANG, K.,LI, P. Y., YU, J. A., XU, W., SHAN, H. L., ZHANG, K. Y., BAO, W. G., FU, X. Q., YANG, S. R.*& WANG, S. F.*2017. A functional variant in the OAS1 gene is associated with Sjogren's syndrome complicated with HBV infection.Scientific Reports,7,9. |
43. TENG, S. Y., WANG, Y.,LI, P. Y., LIU, J. H., WEI, A. H., WANG, H. T., MENG, X. K., PAN, D. & ZHANG, X. M.*2017. Effects ofRtype andStype ginsenoside Rg3 on DNA methylation in human hepatocarcinoma cells.Molecular Medicine Reports,15,2029-2038. |
44. LI, W., ZHANG, X. R., XIN, Y. F., XUAN, Y. X., LIU, J. P.,LI, P. Y. & ZHAO, Y. Q.*2016. Oral subchronic toxicity evaluation of a novel antitumor agent 25-methoxydammarane-3, 12, 20-triol fromPanax notoginsengin Sprague-Dawley rats.Regulatory Toxicology and Pharmacology,77, 240-251. |
45. ZHAO, Q.,LI, P. Y., JIANG, J. & HU, P.*2016. Pharmacokinetics of Single Ascending Doses and Multiple Doses of 20(S)-Ginsenoside Rg3 in Chinese Healthy Volunteers.European Journal of Drug Metabolism and Pharmacokinetics, 41,845-853. |
46. XIONG, L. X., XIE, J. S., SONG, C. X., LIU, J. P., ZHENG, J. T., LIU, C. G., ZHANG, X. T.,LI, P. Y.*& WANG, F.* 2015. The Activation of Nrf2 and Its Downstream Regulated Genes Mediates the Antioxidative Activities of Xueshuan Xinmaining Tablet in Human Umbilical Vein Endothelial Cells.Evidence-Based Complementary and Alternative Medicine. |
47. ZHENG, Q., LI, Z., LIU, J. P., HAN, L., ZHANG, N. Q., ZHANG, H., CHEN, J. L. &LI, P. Y.*2016. Two new dammarane-type triterpene sapogenins from Chinese red ginseng.Natural Product Research,30,95-99. |
48. HAN, L., LI, Z., ZHENG, Q., LIU, J. P. &LI, P. Y.*2016. A new triterpenoid compound from stems and leaves of American ginseng.Natural Product Research,30, 13-19. |
49. ZHAO, T., LIU, J. P., DONG, A., XIAO, L. &LI, P. Y.*2015. Synthesis of functionalized CdTe/ZnS nanoparticles as probes for norfloxacin fluorescence detection.Chalcogenide Letters,12,677-682. |
50. HAN, L., LIN, M. Y., ZHENG, Q., LIU, H. Y., LIU, H. Y., DONG, G., LIU, J. P.*&LI, P. Y.*2014. A new epimer of ocotillol from stems and leaves of American ginseng.Natural Product Research,28,935-939. |
51. YAN, Z. W., LIU, J. P., LU, D., NARLAWAR, R., GROUNDWATER, P. &LI, P. Y.*2014. Two new ceramides from the fruit pulp ofAcanthopanax senticosus(Rupr. et Maxim) Harms.Natural Product Research,28,144-149. |
52. LU, J., LI, G. Y., HUANG, J., ZHANG, C., ZHANG, L., ZHANG, K.,LI, P. Y., LIN, R. C. & WANG, J. H.*2014. Lathyrane-type diterpenoids from the seeds ofEuphorbia lathyris.Phytochemistry,104,79-88. |
53. HUO, J., WANG, H., HU, P., LI, P., LIU, J. & JIANG, J.* 2013. Determination of pseudo-ginsenoside GQ in human plasma by high performance liquid chromatography-tandem mass spectrometry.Biomedical Chromatography,27,1701-1707. |
54. QIU, N. N., HU, J., LIU, J. P., WANG, F. &LI, P. Y.*2013. Preparation and Cytotoxic Activities of Fatty Acid Derivatives of 20(S)-Protopanaxatriol. Letters in Drug Design & Discovery,10, 402-409. |
55. LIU, J. P., TIAN, X., LIU, H. Y., ZHANG, Q. H., LU, D.,LI, P. Y.& ZHAO, C. F.* 2013. Two novel dammarane-type compounds from the leaves and stems ofPanax quinquefoliumL.Journal of Asian Natural Products Research,15, 974-978. |
56. LIN, M. Y., GAO, H. M., LIU, J. P., HAN, L., ZHANG, Q. H. &LI, P. Y.*2013. UPLC-MS/MS determination and pharmacokinetic study of 26-OH-panaxadiol in rat plasma.Analytical methods,5,6656-6662. |
57. GAO, H. M., LI, Z.,LI, P. Y., LIN, M. Y., HAN, L., WANG, F. & LIU, J. P.*2013. Determination of Pseudoginsengenin DQ in rat plasma by UPLC-MS/MS and application of the method in a pharmacokinetic study.Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences,933,1-7. |
58. HUANG, J., HAN, H. Y., LI, G. Y., WANG, H. Y., ZHANG, C., ZHANG, K., TAN, Y.,LI, P. Y.*& WANG, J. H. 2013. Two new terpenoid benzoates with antitumor activity from the roots ofFerula dissecta.Journal of Asian Natural Products Research,15, 1100-1106. |
59. XIE, S. A., LI, G. Y., HUANG, J.*, ZHENG, Y. X., WANG, H. Y., ZHANG, K., GAO, H. Y., TAN, Y., CHEN, W., CHEN, H.,LI, P. Y.& WANG, J. H. 2013. A new flavanol fromCynomorium songaricum.Journal of Asian Natural Products Research,15,413-416. |
60. LU, D., LIU, J. P., ZHAO, W. J. &LI, P. Y.*2012. Chronic toxicity of ginsenoside Re on Sprague-Dawley rats.Journal of Ethnopharmacology,144, 656-663. |
61. LU, D.,LI, P. Y.& LIU, J. P.*2012. Quinquenoside F6, a new triterpenoid saponin from the fruits ofPanax quinquefoliumL.Natural Product Research,26, 1395-1401. |
62. LIU, J. P., LU, D., NICHOLSON, R. C., ZHAO, W. J.,LI, P. Y.& WANG, F.* 2012. Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: A 26-week intramuscular repeated administration study in rats.Food and Chemical Toxicology,50,3388-3396. |
63. ZHAO, Y., LIU, J. P., LU, D.,LI, P. Y.*& ZHANG, L. X.*2012. Two new xanthones from the pericarp ofGarcinia mangostana.Natural Product Research,26,61-65. |
64. LIU, J. P., WANG, F.,LI, P. Y.& LU, D.*2012. A new ocotillol-type triterpenoid saponin from red American ginseng.Natural Product Research,26, 731-735. |
65. LIU, J. P., LU, D. &LI, P. Y.*2012. A novel hexanordammarane glycoside from the leaves and stems ofPanax quinquefoliumL.Natural Product Research,26, 744-748. |
66. LIU, J. P., LU, D., NICHOLSON, R. C.,LI, P. Y.& WANG, F.*2011. Toxicity of a novel anti-tumor agent 20(S)-ginsenoside Rg3: A 26-week intramuscular repeated administration study in Beagle dogs.Food and Chemical Toxicology,49,1718-1727. |
67. LIU, J. P., LU, D. &LI, P. Y.*2011. Two new dammarane-type triterpene saponins from red American ginseng.Journal of Asian Natural Products Research,13,198-204. |
68. LI, N.*, HUANG, Y., XIAO, W., LIU, J. P.*, LI, X. &LI, P. Y.2011. Synthesis and Cytotoxic Activities of New Fatty Acid Esters of 20(S)-Protopanaxadiol. Zeitschrift Fur Naturforschung Section C-a Journal of Biosciences,66,199-204. |
69. ZHAO, Y., LIU, J. P., LU, D.,LI, P. Y.*& ZHANG, L. X.*2010. A new antioxidant xanthone from the pericarp of Garcinia mangostana Linn.Natural Product Research,24, 1664-1670. |
70. YAN, Z. W., LIU, J. P., LU, D., GROUNDWATER, P., HE, C. Y. &LI, P. Y.*2010. A new 3,4-seco-lupane-type triterpenoid from the pulp ofAcanthopanax senticosus(Rupr. et Maxim) Harms.Natural Product Research,24,1523-1527. |
71. LU, D., LIU, J. P. &LI, P. Y.*2010. Dihydrophenanthrenes from the stems and leaves ofDioscorea nipponicaMakino.Natural Product Research,24,1253-1257. |
72. LU, D., LIU, J. P., LI, H. J. & LI, P. Y.*2010. Phenanthrene derivatives from the stems and leaves ofDioscorea nipponicaMakino.Journal of Asian Natural Products Research,12,1-6. |
73. YAN, Z. W., LIU, J. P., LU, D., XUE, J. F. &LI, P. Y.*2009. A new bile acid from the bile of Anser anser.Natural Product Research,23,1312-1315. |
74. ZHAO, Y., LIU, J. P., LU, D. &LI, P. Y.*2007. A novel cycloartane triterpene glycoside from the seeds ofCassia sopheraL.Natural Product Research,21,494-499. |
75. LIU, J. P., LU, D., ZHAO, Y.,LI, P. Y.*& LI, X. 2007. A new semisynthetic ocotillol-type saponin and resuscitation of haemorrhagic shock.Journal of Asian Natural Products Research,9,103-113. |
Books: |
1. TANG, H. Y., XU, S., G.,LI, P. Y.2020.Organic Chemistry, Beijing Industry Press. |
2.LI, P. Y., LIU, J. P. 2020.Ginseng Nutritional Components and Functional Factors, Springer. |
3.LI, P. Y., LIU, J. P., WANG, F., 2020.Xuemai Shuangzhi-Xueshuan Xinmaining Tablets Modern Research,People's Medical Publishing Press. |
4.LI, P. Y., LIU, J. P., FENG H. 2019.Zhongtonghuazheng Capsules-Pharmacy, Pharmacodynamics and Clinical Research, Chemical Industry Press. |
5.LI, P. Y., LIU, J. P. 2017.Ginseng Nutritional Ingredients and Functional Factors, Chemical Industry Press. |
6.LI, P. Y., LIU, J. P., LU, D. 2012.Ginsenoside NMR Standard Atlas, Chemical Industry Press. |
7. ZHANG, H.,LI, P. Y., FENG, J., LIU, J. P. 2010.Efficacy and Scientific Administration of Ginseng.Jilin Publishing Group Co., Ltd. |
8. ZHANG, J. T.,LI, P. Y., LU D., LIU, J. P. 2008.Ginseng Crown Herbs-Research Progress in Ginseng Chemistry, Biological Activity and Pharmacokinetics. Chemical Industry Press. |
9. ZHANG, J. T.,LI, P. Y., LU, D., LIU, J. P. 2006.The Chemistry, Metabolism and Biological Activities of Ginseng, Chemical Industry Press. |
10.LI, P. Y., ZHAO, CH. F., LIU, J. P. 2006.Research Progress on the Chemical Composition and Biological Activity of Kiwi Fruit, Jilin Science and Technology Press. |
Pantents for inventions: |
1. WU, F. L.,LI, P. Y., LIU, J. P.,WANG, D. H., GUO, W. Y., LI,Y. J. 2019.HPLC fingerprint chromatogram detection method for capsules capable of relieving pain and removing blood stasis. CN108445125B. |
2. XIONG, L. Z., WANG, F., ZHANG, C., LU, Y. J., WANG, G. Q., GUAN, X. W., CHEN, F., ZHENG, J. Q., WANG, T.,LI, P. Y.2015.Application of compound in preparation of medicine for treating chronic obstructive pulmonary disease. CN105147670A. |
3. LI, P. Y., ZHENG, Q., LIU, J. P., ZHANG, N.Q., WANG, Z.Z., ZHU, H.L., CHEN, J.L., ZHANG, H.2015.(20S,25R)-dammar-20,25-epoxy- 3β,12β,26,24β-tetrol and extracting method and medical applications thereof. CN104761609A. |
4. HAN, L.,LI, P. Y., LIU, J. P., LI, Z., ZHENG, Q. 2015.Dama-20S, 25S-epoxy-3β, 12β, 26-triol as well as extracting method and pharmaceutical application thereof.CN104693262A. |
5. ZHENG. Q.,LI, P. Y.,ZHANG, Q. H. 2014.Novel macamide compounds as well as synthetic method and medical application of novel macamide compounds. CN103980146A. |
6. LI, P. Y., QIU, N. N., LIU, W. J., YANG, Y. F. 2013.Functional ginseng, preparation method and application of ginseng for treating male sexual dysfunction. CN103271959A. |
7. LI, P. Y., SU, H., LIU, H. Y., DONG, G., LI, Z., CHEN, J.,TIAN, X., ZHANG, Q. H., LIU,J. P.2013. Pseudoginsenoside R1 and extraction method thereof, and applications of pseudoginsenoside R1 drug. CN103193847A. |
8. LI. P. Y., LIN, M. Y., HAN, L., ZHENG, Q., LI, Z., LIU, H. Y., WANG, C. Z., LIU, J. P. 2013.Pseudoginsenoside RT6 and extraction method thereof, and applications of pseudoginsenoside RT6 drug. CN103193848A. |
9. LI, P. Y., LIU, J. P. 2013.Application of extract of American ginseng fruit. CN102988441A. |
10. LI, P. Y., LU, D., WANG, P., LIU, C. G., WANG, S.P., JIN, X.Q.2012. Drug combination. CN102688231A. |
11. HAO, X. H., REN, Y. Y., ZHANG, Q. H., LIN, M. Y., LIU, H. Y.,LI, P. Y., LU, D., LIU, J. P.Dammar-20S, 25R-epoxy-3β, 12β, 26-triol and extraction method and drug use thereof. CN102329360A. |
12. Zhong, F. L., LI,P. Y., WANG, X. L. 2011.Rosa davurica total flavone extract, its extracting method and its medical use. CN102228539A. |
13. LI, P. Y., LIU, J. P., REN, Y. Y., LIU, C. G., HU, J. H., DU, X. J.Preparation method of 24(R)-ocotillol DQ and pharmacal application thereof. CN102050860A. |
14. ZHONG, F. L.,LI, P. Y., LIU, J. P., LU, D., ZHAO, Y., WANG, X. L. 2011.Transplanted wild ginseng ginsenoside B as well as extraction method and medical application thereof. CN102050864A. |
15. LI, P. Y., LIU, J.P.,TIAN, X., LIU, C.G., ZHU, J.Z., LI, F.2011.Method for extracting pseudoginsenoside RT5 and medical application. CN102010456A. |
16. LI, P. Y., LIU, J.P., LIU, C. G., JIN, L.Q., ZHANG, G.M., YAN, Z.L., CHI, X.J. 2011.Application of pseudo-ginsenoside GQ. CN102008498A. |
17. LI, P. Y., LU, D., WANG, P., LIU, C. G., WANG, S. P., JIN, L. Q.Girald daphne bark leaf extract and medicinal application thereof. CN102008599A. |
18. LI, P. Y., LIU, J. P., LU, D., LIU, C. G., DU, X. J., LI, F. 2011.20(R)-pseudoginsenoside F11 as well as extraction method and medical purpose thereof. CN101967170A. |
19. LI, P. Y., LIU, J. P., LU, D., LIU, C. G., DU, X. J., LI, F. 2011.Ginsenoside R10, extraction method and pharmaceutical use thereof. CN101948497A. |
20. LI, P. Y., LIU, J. P., LU, D., LIU, C. G., DU, X. J., LI, F. 2011.Pseudo-ginsenoside G2, extraction method and drug application thereof. CN101948498A. |
21. LI, P. Y., LIU, J. P., LU, D., LIU, C. G., DU, X. J., LI, F. 2011.Pseudoginsenoside G1 and extraction method and medicinal applications thereof. CN101948499A. |
22. LIU, J. P.,LI, P. Y., LU, D., LI, Y. J. 2010.American ginseng ginsenoside F5ab and extraction method and medicinal application thereof. CN101928320A. |
23. LI, P. Y., LIU, J. P., LU, D.,2010.Application of gartanin compound in preparing medicaments for treating hyperlipidemia. CN101869559A. |
24. LU, D.,LI, P. Y., LIU, J. P. 2010.American ginseng saponin F6 as well as extraction method and medical application thereof. CN101863945A. |
25. LI, P. Y., LIU,C. G., JIN, L. Q., WANG, F. W., WANG, W. J., YAN, Z. L., ZHANG, G. M. 2010.Goose gall extract, preparation method and medicine use thereof. CN101810643A. |
26. ZHAO, W. J., NI, J. S.,LI, P. Y.2010.Application of 20(S)-ginsenoside Rg3 in preparation of medicines for treating non-small cell lung cancer. CN101732332A. |
27. LIU, J. P.,LI, P. Y., LU. D., XUE. J. F. 2009.Hazel endothelin and extracting method and drug application thereof. CN101613340. |
28. LI, P. Y., LU. D., LIU, J. P. 2009.Medicine composition for regulating blood fat. CN101584685. |
29. LI, P. Y., LIU, J. P., LU, D., ZHOU, M. J. 2009.Application of acanthopanax fruit extractive in preparing medicament for treating hyperlipoidemia. CN101584719. |
30. LIU, J. P.,LI, P. Y., LU, D., XUE, J. F. 2009.Hazelnut element B, extracting method and pharmaceutical use thereof. CN101550125. |
31. LU, D.,LI, P. Y., LIU, J. P., LI, H. J. 2009.5-methylol-furfural-5-furfural-methanol, preparation method thereof and medical application thereof. CN101544624. |
32. LU, D.,LI, P. Y., LIU, J. P., LI, H. J. 2009.Dimer (5-methylol-furfural), synthetic method thereof and medical application thereof. CN101544654. |
33. LI, P. Y., LIU, J. P., LU, D., DU, X. J. 2009.Medical application of psuedo-ginsenoside F11. CN101524358. |
34. LI, P. Y., LIU, J. P. 2009.Semi-synthetic method of pseudo-ginsenoside F11. CN101519419. |
35. ZHAO, W. J., YAN, W. Q.,LI, P. Y., ZHANG, J. T. 2009.Use of bilobalide B in preparing medicine for promoting nerve cell regenerate. CN101396355. |
36. LI, P. Y., LU, D., LU, A. P., LIU, J. P., DU, X. J. 2008.Simulated moving bed chromatography separation of 20(S) and 20(R)-ginsenoside Rg3 enantiomer.CN101230080. |
37. LI, P. Y., LIU, J. P. 2005.Pseudoginsenoside Pdq and its semi-synthesis process and medicine use. CN1706862. |
38. LI, P. Y., ZHAO, W. J., LIU, J. P. 2004.Herminium's triochistisaponine extract and its extraction refining method and its medical use.CN1537863. |
39. ZHANG, J. T.,LI, P. Y., ZHAO, W. J. 2004.Application of ginsenoside Re for preparing medicine for curing dysmnesia.CN1498621. |
40. LI, P. Y., LIU, J. P., LU, D. 2004.Extract of american ginseng fruit saponin, extracting and refining method and medicinal use thereof.CN1482136. |
41. LI, P. Y., LI, P. 2003.Use of total polygalin in preparing medicine for promoting gastrointestinal peristalsis.CN1425384. |
42. LI, P. Y., ZHAO, W. J., WU, J. X. 2000.Semisynthesizing method for 20(S)-ginsenoside Rg3, and use in medicine.CN1243128. |
43. LI, P. Y., ZHAO, W. J. 2000.Process for extracting ginsenoside Re, and use of medicine thereof.CN1242374. |
