办公地点

Room 505,School of Pharmaceutical Sciences

药学院505

办公电话

0431-85619725

邮箱

guanqx@jlu.edu.cn

教育背景

2011-2012 Visiting Scholar, Northeastern University

2003-2008 Doctor,Biochemistry and Molecular Biology, School of life Sciences,Jilin University

1997-2000 Master,Pharmaceutics,School of Pharmaceutical Sciences,Yanbian University

1993-1997 Bachlor,Pharmacy,School of Pharmaceutical Sciences,Yanbian University

2011-2012 美国东北大学 访问学者

2003-2008 吉林大学生命科学学院 博士研究生

1997-2000 延边大学药学院,药剂学 硕士研究生

1993-1997 延边大学药学院药学系 本科生

工作经历

2018- Professor & doctoral supervisor,School of Pharmaceutical Sciences,Jilin University

2013- Professor,School of Pharmaceutical Sciences,Jilin University

2008-2013 Vice Professor & master supervisor,School of Pharmaceutical Sciences,Jilin University

2002-2008 Lecturer,School of Pharmaceutical Sciences,Jilin University

2000-2002 Asisstant,School of Pharmaceutical Sciences,Jilin University

2018- , 吉林大学, 药学院, 教授/博士生导师

2013- , 吉林大学, 药学院, 教授

2008-2013,吉林大学, 药学院, 副教授/硕士生导师

2002-2008,吉林大学, 药学院, 讲师

2000-2002,吉林大学, 药学院, 助教

主讲课程

Pharmaceutics

药剂学

研究领域

Pharmaceutics: Nanotechnology;Targeted Delivery Systems;Development of New Drugs;Improvment of Product Quality;Development of Health Food; Research and Development ofCosmetics

药剂学：纳米技术；靶向递药；新药开发；产品质量提升；保健食品开发；化妆品研发

科研成果

Representative Publications:

1.Guangyuan Zhang, Long Huang, Ji Wu, Yuran Liu,Qingxiang Guan(通讯作者).Doxorubicin-loaded folate-

mediated pH-responsive micelle based on Bletilla striata polysaccharide: release mechanism, cellular

uptake mechanism, distribution, pharmacokinetics, and antitumor effects.International Journal of

Biological Macromolecules, 2020, 164: 566-577.

2.YuranLiu, Cheng Sun, Guangyuan Zhang, Ji Wu, Long Huang, Jin Qiao,Qingxiang Guan(通讯作者). Bio-

responsive Bletilla striata polysaccharide-based micelles for enhancing intracellular docetaxel

delivery.International Journal of Biological Macromolecules, 2020, 142: 277–287.

3.Yuran Liu, Ji Wu, Long Huang, Jin Qiao, Ning Wang, Di Yu, Guangyuan Zhang, ShangminYu,Qingxiang

Guan(通讯作者).Synergistic effects of antitumor efficacy via mixed nano-size micelles of

multifunctional Bletilla striata polysaccharide-based copolymer and D-α-tocopheryl polyethylene glycol

succinate.International Journal of Biological Macromolecules, 2020, 154: 499–510.

4.Guangyuan Zhang, Jin Qiao, Xin Liu, Yuran Liu, Ji Wu, Long Huang, Danyang Ji,Qingxiang Guan(通讯作

者).Interactions of self-assembled Bletilla Striata polysaccharide nanoparticles with bovine serum

albumin and biodistribution of its docetaxel-loaded nanoparticles.Pharmaceutics, 2019, 11(1), 43,

https://doi.org/10.3390/pharmaceutics11010043.

5.Jin Qiao, Danyang Ji, Shilin Sun, Guangyuan Zhang, Xin Liu, Bingxue Sun,Qingxiang Guan(通讯作

者). Oral Bioavailability and Lymphatic Transport of Pueraria Flavone-Loaded Self-Emulsifying Drug-

Delivery Systems Containing Sodium Taurocholate in Rats.Pharmaceutics, 2018, 10(3):147,

doi:10.3390/pharmaceutics10030147.

6.Dandan Sun, Miao Wang, Danyang Ji, Jin Qiao, Tong He, Xin Liu,Qingxiang Guan(通讯作者).Synthesis of

a reduction-sensitive Bletilla striata polysaccharide amphiphilic copolymer.Chinese chemical Letters，

2018, 29(6) :831–833.

7.Hang Gao, Miao Wang, Dandan Sun, Shilin Sun, Cheng Sun, Jianguo Liu,Qingxiang Guan(通讯作者).

Evaluation of the cytotoxicity and intestinal absorption of a self-emulsifying drug delivery system

containing sodium taurocholate.European Journal of Pharmaceutical Sciences 2017,106:212-219.

8.Qingxiang Guan, Guangyuan Zhang, Shilin Sun, Hongbo Fan, Cheng Sun, Shaoyuan Zhang.Enhanced Oral

Bioavailability of Pueraria Flavones by a Novel Solid Self-microemulsifying Drug Delivery System

(SMEDDS) Dropping Pills.Biol. Pharm. Bull.2016,39:762–769.

Patents:

Qingxiang Guan,Tianmu Lin, Jinwen Lu,Qian Chen. preparation and formula of a lutein ocular delivery system based on nanovesicles entrapped in an in situ forming gel. ZL201110144619.6. 2013-01-23.